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- ***********************************
- * Ribosomal protein S18 signature *
- ***********************************
-
- Ribosomal protein S18 is one of the proteins from the small ribosomal subunit.
- subunit. In Escherichia coli, S18 has been involved in aminoacyl-tRNA binding
- [1]. It appears to be situated at the tRNA A-site of the ribosome. It belongs
- to a family of ribosomal proteins which, on the basis of sequence similarities
- [2], groups:
-
- - Eubacterial S18.
- - Plant chloroplast S18.
- - Cyanelle S18.
-
- As a signature pattern, we selected a conserved region in the central section
- of the protein. This region contains two basic residues which may be involved
- in RNA-binding.
-
- -Consensus pattern: I-[DY]-Y-x(2)-[LIVM]-x(2)-[LIVM]-x(2)-[FY]-[LIVM]-[ST]-
- [DE]-x-G-K-[LIVM](2)-x(2)-R-[LIVM]
- -Sequences known to belong to this class detected by the pattern: ALL, except
- for Euglena gracilis S18.
- -Other sequence(s) detected in SWISS-PROT: NONE.
- -Last update: June 1994 / Text revised.
-
- [ 1] McDougall J., Choli T., Kruft V., Kapp U., Wittmann-Liebold B.
- FEBS Lett. 245:253-260(1989).
- [ 2] Otaka E., Hashimoto T., Mizuta K.
- Protein Seq. Data Anal. 5:285-300(1993).
-